Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1)
- Target
- ST6GAL1
- Molecular classification
- Enzyme, Glycosyltransferase, Sialyltransferase, Type II membrane protein
01
Overview
Sialyltransferase CD75/ST6GAL1 is an α2–6-sialylating enzyme crucial for modifying glycoconjugates involved in immune regulation. Its expression pattern makes it valuable both biologically—in modulating immunity—and clinically—as a diagnostic marker especially relevant to hematopathology. It catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates, specifically forming α2,6 linkages on glycoproteins and glycolipids.
- Other names
- CD75Sialyltransferase CD75
02
Mechanism of action
N/A
03
Biological functions
SialylationCellular recognitionCell signalingCell-cell interactionsAntigen presentationImmune regulation
04
Disease associations
Cancer (glioblastomas, astrocytomas, lymphomas)Lymphocyte-predominant Hodgkin’s disease
05
Biomarkers
B-cell phenotypes in lymphoid tissuesReed-Sternberg cells of lymphocyte-predominant Hodgkin’s disease
Beyond the preview
Go deeper on Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1).