BICRA like chromatin remodeling complex associated protein (BICRAL)

BICRA like chromatin remodeling complex associated protein (BICRAL) is a protein-coding gene product that serves as a core component of the SWI/SNF chromatin remodeling complex, specifically the non-canonical GBAF subcomplex[6][10]. Chromatin remodeling complexes alter the structure of chromatin to regulate access to DNA for transcription, replication, and repair. BICRAL participates in protein binding and gene regulation processes essential for cellular differentiation and tissue-specific gene expression. It is expressed widely in mammalian tissues and is highly conserved across species, with alternative names reflecting its discovery and characterization by various research groups[4][9][12]. Unlike other SWI/SNF complex components or interaction partners like BRD4, BICRAL is not a receptor, enzyme, or known therapeutic target, and no drugs are currently recognized to modulate its function directly[6][10]. If further information is required regarding its involvement in disease or interaction with drugs, it will be necessary to consult more detailed functional genomics or proteomics databases.

Other names

GLTSCR1LKIAA0240SMARCK2BRD4-interacting chromatin-remodeling complex-associated protein-likeBC032203 (mouse)