Target intelligence / Profile preview

Bile Duct Smooth Muscle

Molecular classification
Smooth Muscle
01

Overview

Bile duct smooth muscle refers to the specialized smooth muscle tissue found in the walls of the bile ducts, which are tubular structures responsible for transporting bile from the liver and gallbladder to the duodenum. This smooth muscle is essential for regulating bile flow and ensuring proper digestive function.

Other names
Biliary smooth muscleSphincter of Oddi muscleBile duct wall muscle
02

Mechanism of action

Regulates transport of bile by contracting or relaxing to control lumen diameter. Seals off sections (e.g., via sphincters) to prevent backflow or regulate timing of secretion into intestines. Contributes to peristaltic movements that propel bile through ducts toward its destination.

03

Biological functions

Regulation of bile flowControl of lumen diameterPeristalsisSphincter control
04

Disease associations

Sphincter of Oddi dysfunction/dyskinesiaGallstone diseaseBiliary dysmotility
05

Safety considerations

Adverse effects of drugs affecting smooth muscle contractilityPotential for biliary spasm or obstruction
06

Interacting drugs

Cholecystokinin (CCK)

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