Biomarkers of metabolic and mitochondrial function

"Biomarkers of metabolic and mitochondrial function" is a broad descriptive term for various molecules and measurable features in biological fluids (like blood, urine, CSF) that indicate the status of mitochondrial health or metabolic function. These are not molecular targets for drugs, but rather diagnostic tools used to detect, monitor, and stratify diseases related to mitochondrial dysfunction and abnormal metabolism. Commonly studied biomarkers include lactate, pyruvate, FGF-21, and GDF-15, though many others exist. These markers can help support diagnosis (often in concert with genetic or imaging studies), inform prognosis, and track disease status in metabolic and mitochondrial diseases. However, many are not specific and require further validation for widespread clinical use[1][2][4].

Other names

Biomarkers of mitochondrial diseaseMetabolic biomarkersMitochondrial dysfunction biomarkers