Bladder

The **bladder** is a hollow muscular organ in the pelvis that stores urine produced by the kidneys before it is excreted from the body. It is not a molecule, receptor, enzyme, transporter, or any other type of therapeutic target at a molecular level. In biomedical research and drug development contexts—especially oncology—the term "bladder" usually refers to *bladder cancer* when discussing targets for therapy. However, actual therapeutic targets are specific proteins or pathways within bladder cells that drive disease processes. For example: - In **bladder cancer**, targeted therapies focus on molecules such as fibroblast growth factor receptors (*FGFR2*, *FGFR3*), Nectin-4, EpCAM, VEGF/VEGF-R pathways[1][3][5][7]. - Drugs like erdafitinib inhibit FGFRs in tumors with relevant gene alterations[1][7][8]. - Antibody-drug conjugates like enfortumab vedotin target Nectin-4 on tumor cells[1]. Thus, > The entry "Bladder" does **not** refer to a valid molecular therapeutic target but rather an anatomical structure. For structured data extraction regarding drug targets in this context, you should use specific molecules/proteins expressed in bladder tissue or tumors (e.g., "Fibroblast growth factor receptor 3") instead of "Bladder"[1][5][6]. If you need information about actual druggable targets relevant to diseases affecting this organ—such as those involved in urothelial carcinoma—please specify those proteins/receptors by name.

Other names

BladderUrinary bladder