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The concept of “blood circulation improvement via traditional Chinese medicine theory” refers to a TCM-based therapeutic strategy rather than a single molecular target. This approach centers on using herbal medicines and therapies to “activate blood circulation and remove blood stasis,” aiming to prevent or treat disorders such as microvascular complications of diabetes, cardiovascular diseases, and atherosclerosis. Frequently used botanicals, including Salvia miltiorrhiza (Danshen), Panax notoginseng, Ligusticum chuanxiong, and Carthamus tinctorius, exert multiple effects: anti-platelet aggregation, vascular endothelial protection, and improvement in blood rheology. Modern research has drawn parallels between this TCM strategy and antiplatelet or anticoagulant therapies in Western medicine. However, because this is a broad TCM principle—not a discrete molecule, protein, or receptor—it is not appropriate to categorize it under canonical therapeutic targets used in pharmacology or drug discovery[1][2][4][6].
Antiplatelet effect, Improvement of microcirculation, Endothelial protection, Reduction of oxidative stress, Lipid metabolism regulation, Anti-inflammatory effect
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