Target intelligence / Profile preview

Blood Coagulation

Molecular classification: Biological Process

Overview

Blood coagulation is a critical physiological process that prevents excessive bleeding when blood vessels are injured. It involves a complex cascade of enzymatic reactions and cellular interactions, ultimately leading to the formation of a stable fibrin clot that seals wounds and allows for tissue repair. The process is tightly regulated to ensure both effective hemostasis and prevention of unwanted clot formation.

Other names: ClottingHemostasisCoagulation Cascade

Mechanism of action

Various, depending on the specific drug. Anticoagulants inhibit clotting factors, antiplatelet drugs inhibit platelet aggregation, and thrombolytics dissolve existing clots.

Biological functions

HemostasisWound healingPrevention of blood lossVascular repair

Disease associations

ThrombosisThrombophiliaHemophiliaStrokePulmonary embolismBleeding disorders

Safety considerations

Bleeding riskThrombocytopeniaDrug interactionsHeparin-induced thrombocytopenia (HIT)Thromboembolic events (with inappropriate anticoagulation)

Interacting drugs

Anticoagulants (e.g., Warfarin, Heparin, Direct Oral Anticoagulants)

2 more in the full profile.

Biomarkers

Prothrombin time (PT)Activated partial thromboplastin time (aPTT)International normalized ratio (INR)Platelet countD-dimer

Beyond the preview

Go deeper on Blood Coagulation.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Blood Coagulation.

Explore the full profile