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Blood rheology parameters refer to the measurable physical characteristics that determine how blood flows under various physiological and pathological conditions. Key parameters include whole blood viscosity, plasma viscosity, red blood cell deformability, red blood cell aggregation, and hematocrit[1][3][5][7]. These parameters collectively influence vascular resistance, tissue perfusion, and oxygen delivery. Abnormal blood rheology is associated with increased risk of cardiovascular disease, impaired microcirculation, and various blood disorders. Since these parameters are not discrete molecules but are emergent properties of blood composition and cell mechanics, they are not “targets” for drugs or molecular interventions but are vital measurements and biomarkers in both research and clinical practice.
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