Target intelligence / Profile preview

Blood stasis (BS)

Target
BS
Molecular classification
Other (TCM syndrome; not classified under molecular families such as receptor, enzyme, transporter, etc.)
01

Overview

Blood stagnation, also known as blood stasis, is a diagnostic concept in traditional Chinese medicine referring to impaired blood flow, pooling, or accumulation within the body. It is believed to be an underlying cause of many symptoms and diseases, including cardiovascular disorders, gynecological problems, pain syndromes, and even cancer, according to TCM texts. The syndrome is diagnosed by assessing characteristic signs such as purplish skin, local pain, and poor circulation, along with medical history and subjective practitioner judgment. TCM treatments aim to "move blood," such as acupuncture, herbal medicine, cupping, and moxibustion. In Western medicine, blood stagnation is sometimes likened to conditions involving hypercoagulability, thrombosis, or poor perfusion, but it lacks a direct molecular or anatomical equivalent. There are no standardized biomarkers or objective diagnostic tools for blood stasis; efforts to translate it into modern biomedical terms remain largely speculative.

Other names
blood stagnationblood stasis syndromeBSS
02

Mechanism of action

"Activating blood circulation and removing blood stasis" (TCM claim for herbs and acupuncture, not a direct molecular mechanism); Platelet inhibition/thrombolysis (aspirin, heparin in Western medicine)

03

Biological functions

Other (TCM pathophysiology; loosely associated with impaired blood flow/circulation, but not a directly mapped biological function)
04

Disease associations

Cardiovascular disease (e.g., coronary heart disease, stroke)Pain syndromes (e.g., chronic pain, dysmenorrhea, endometriosis)Gynecological disordersCancer (TCM theory suggests a link between blood stasis and tumor development)Other (TCM assigns roles in many conditions; see above)
05

Safety considerations

Lack of objective diagnostic criteria leads to variable outcomesHerbal treatments can pose safety risks (e.g., interactions, toxicity)Potential misdiagnosis of real underlying diseases as "blood stagnation"
06

Interacting drugs

XueFu Zhuyu

5 more in the full profile.

07

Biomarkers

None established; diagnosis is subjective and based on signs/symptoms (e.g., purplish tongue, fixed pain), not on quantifiable molecular markers

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