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Blood stasis resolution via herbal synergy

Molecular classification
Other (therapeutic principle, not a molecule/receptor/enzyme/etc.)
01

Overview

Blood stasis resolution via herbal synergy is a traditional Chinese medicine therapeutic principle, not a molecular target. It denotes the synergistic use of herbal formulas (often combined with conventional anticoagulants like aspirin or heparin) to promote blood flow, reduce stasis and viscosity, improve tissue perfusion, and address pathological states associated with impaired circulation such as stroke, cardiovascular disease, thrombosis, cancer adjuncts, and certain inflammatory disorders. Diverse herbs with distinct but complementary actions are combined to target multiple physiological pathways, reflecting TCM's holistic approach. These effects are sometimes mirrored by drugs like aspirin or heparin, which have anticoagulant and blood flow-promoting activities aligned with TCM concepts. However, "Blood stasis resolution via herbal synergy" should not be listed as a molecule, receptor, enzyme, or transport protein in research databases; it is a clinical strategy or multi-modal therapy rather than a discrete biological target.

Other names
Blood stasis resolutionBlood-activating and stasis-resolving therapyPromoting Blood Circulation and Removing Blood Stasis Therapy (PBCRBST)
02

Mechanism of action

Multicomponent synergy targeting blood flow and stasis via: Inhibition of platelet aggregation; Reduction of blood viscosity; Anticoagulation (as with heparin/aspirin); Improvement of microcirculation; Repair of necrotic nerve cells (TCM conceptual); Regulation of endothelial cell function; Multi-target regulation typical of TCM herbal combinations

03

Biological functions

Blood circulation enhancementAnticoagulationReduction of blood viscosityInhibition of platelet aggregationVascular protectionNeuroprotection
04

Disease associations

Cardiovascular diseaseCerebrovascular disease (e.g. stroke/cerebral infarction)Thrombosis/hypercoagulable statesCancer (adjunct role)Inflammatory diseaseOther (according to TCM theory)
05

Safety considerations

Risk of bleeding (anticoagulant herbs/herb-drug combinations)Aspirin resistance (may require adjunct therapy)Polypharmacy/adverse herb-drug interactionsOveruse may cause Yin injury or bleeding per TCM principles
06

Interacting drugs

Herbal formulas (e.g. Buyang Huanwu decoction, Naoxintong capsules)

3 more in the full profile.

07

Biomarkers

Blood viscosityPlatelet aggregation markersCholesterol/triglyceride levelsFunctional recovery metrics (e.g. hemiplegic limb function)Quality of life scores

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