BMP7 antisense RNA 1 (BMP7-AS1)

BMP7 antisense RNA 1 (BMP7-AS1) is a long non-coding RNA gene located antisense to the BMP7 gene. It is affiliated with the lncRNA class and is not a protein-coding gene. While the precise biological functions of BMP7-AS1 are not extensively described, lncRNAs are typically involved in the regulation of gene expression at the transcriptional or post-transcriptional level. There is evidence associating the BMP7-AS1 gene with the congenital condition craniosynostosis. Unlike protein targets such as BMP7, BMP7-AS1 is not recognized as a therapeutic target such as a receptor, enzyme, or transporter[3].\n\nBMP7-AS1 is not the same as BMP7, which is a protein of the TGF-β superfamily and a bona fide therapeutic target in several indications such as bone disease and cancer[1][5][7]. BMP7-AS1's role as a therapeutic target is not established, but its potential regulatory influence on BMP7 or other genes could be of research interest[3].

Other names

BMP7-AS1BMP7 antisense RNA 1

Not applicable; no drugs are known to target this lncRNA directly.