Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Bone Marrow Tyrosine Kinase X-linked (BMX)
- Target
- BMX
- Molecular classification
- Non-receptor tyrosine kinase, Enzyme, Tec family kinase
01
Overview
Bone marrow tyrosine kinase on chromosome X (BMX), also known as endothelial/epithelial tyrosine kinase (Etk), is a non-receptor tyrosine kinase belonging to the Tec family. BMX is predominantly expressed in myeloid hematopoietic lineages, endothelial cells, and several types of cancers and plays a role in signal transduction, vascular biology, lymphangiogenesis, and inflammation. It is considered a potential target for cancer therapy due to its role in tumor progression.
- Other names
- Endothelial/epithelial tyrosine kinaseEtk
02
Mechanism of action
Tyrosine kinase inhibition
03
Biological functions
Signal transductionAngiogenesisArteriogenesisLymphangiogenesisInflammation controlCell growthCell differentiation
04
Disease associations
CancerInflammatory disorders
Beyond the preview
Go deeper on Bone Marrow Tyrosine Kinase X-linked (BMX).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Bone Marrow Tyrosine Kinase X-linked (BMX).