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Target intelligence / Profile preview
Bone morphogenetic protein receptor type 1A pseudogene 1 (BMPR1AP1)
- Target
- BMPR1AP1
- Molecular classification
- Pseudogene, Processed pseudogene (retrocopy)
01
Overview
Bone morphogenetic protein receptor type 1A pseudogene 1 (BMPR1AP1) is classified as a processed pseudogene, specifically a retrocopy derived from the BMPR1A gene. Pseudogenes such as BMPR1AP1 structurally resemble protein-coding genes but contain mutations that prevent them from coding functional proteins. BMPR1AP1 is not reported to have established biological or disease-related functions, does not encode an active receptor protein, and no drugs are known to interact with it. While some pseudogenes can regulate their parent genes or other cellular processes at the RNA level (such as acting as RNA decoys or being processed into regulatory RNAs), no such activity has been directly attributed to BMPR1AP1. It is primarily annotated for its homology to BMPR1A and its lack of protein-coding ability[1][3][4][5][6][8].
- Other names
- BMPR1APS1Bone morphogenetic protein receptor, type IA pseudogene 1
02
Mechanism of action
None applicable (pseudogene, no known mechanism of drug action)
03
Biological functions
No established protein-coding function (pseudogenes do not code for functional proteins)May play regulatory roles at the RNA level, such as competing for microRNAs (as seen with other pseudogenes in general, not specifically established for BMPR1AP1)
04
Disease associations
None directly assigned to BMPR1AP1In general, some pseudogenes have been shown to regulate disease-associated genes (e.g., cancer, diabetes) through non-coding mechanisms, but no evidence is available for this pseudogene specifically
05
Safety considerations
None specific (pseudogenes are generally not therapeutic targets, so no safety issues relevant to targeting)
06
Interacting drugs
None (it is not a protein-coding gene, no known drugs interact with this pseudogene)
07
Biomarkers
None established for patient selection or efficacy
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