Bone tissue regeneration

Bone tissue regeneration is a dynamic physiological process involving stem cell activation, differentiation, and coordination between osteoblasts (bone-forming cells), osteoclasts (bone-resorbing cells), osteocytes, immune cells, and endothelial cells. It is regulated by numerous signaling pathways, including BMP, Wnt, TGF-β, and RANKL, as well as transcription factors and extracellular matrix interactions. Bone tissue regeneration underpins natural fracture healing and the biological response to implantable biomaterials, and is the ultimate goal for therapies addressing bone trauma, defects, or diseases such as osteoporosis[1][2][3][4].

Other names

bone regenerationbone repairbone healing