Bordetella bronchiseptica

Bordetella bronchiseptica is a small, Gram-negative, aerobic, motile, rod-shaped bacterium commonly found in the respiratory tract of animals, especially dogs and cats, where it causes highly contagious respiratory disease (kennel cough in dogs, bordetellosis in cats); it can persist in the environment for extended periods and rarely causes infections in humans, primarily infecting the immunocompromised. Its pathogenicity is due to a suite of virulence factors (adhesins such as filamentous hemagglutinin, fimbriae, pertactin; toxins like dermonecrotic toxin; flagella), and its expression of virulence genes is tightly regulated by the BvgAS two-component regulatory system

Other names

Bordetella bronchisepticaB. bronchiseptica

Inhibition of bacterial cell wall synthesis (by certain β-lactams), inhibition of protein synthesis (by tetracyclines and aminoglycosides), lytic activity (by bacteriophages)