Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Boron (B)
- Target
- B
- Molecular classification
- Element, metalloid
01
Overview
Boron is a metalloid element with atomic number 5, properties intermediate between metals and nonmetals. It is essential for plant growth and used in various industrial and materials science applications. Boron exists in amorphous and crystalline forms and forms numerous compounds, including borates and boric acid. Boron is not found as a free element in nature but is present in minerals and volcanic springs. While boron is not a classical therapeutic target, boron-based compounds have applications in medicinal chemistry, such as proteasome inhibition in cancer therapy.
- Other names
- Boronmetallic boron[2][4]boric anhydride (for oxide)boron trioxideboric acidborax (for compounds)[2][4][7]
02
Mechanism of action
Proteasome inhibition for bortezomib (boron atom forms reversible covalent bonds with active site threonine); antifungal, antiseptic, fluxing agent (via boron compounds)
03
Biological functions
Essential micronutrient for plant cell walls[6]involved in certain metabolic processesnot directly involved in signal transduction or classic cellular pathways in animals
04
Disease associations
Some boron compounds are under investigation for cancer (e.g., brain tumours)[6]otherwise, boron itself is not directly implicated as a disease target
05
Safety considerations
Boron toxicity can occur at high levels in humans, affecting metabolism and possibly reproduction[2][6]is essential for plants but can be harmful at excessive concentrations[6]
06
Interacting drugs
bortezomib
07
Biomarkers
No established role for elemental boron itself as a biomarkerboron concentration may be measured for exposure/toxicity[2]
Beyond the preview
Go deeper on Boron (B).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Boron (B).