Target intelligence / Profile preview

Bowel smooth muscle

Molecular classification: Other (Muscle tissue)

Overview

Bowel smooth muscle refers to the smooth muscle tissue found in the walls of the intestines. It plays a crucial role in the movement of food through the digestive tract via peristalsis and segmentation. This muscle type is involuntary and is regulated by the autonomic nervous system and various hormones and neurotransmitters. It is not a specific molecular target but rather a type of tissue involved in various physiological processes and diseases.

Other names: Intestinal smooth muscleGastrointestinal smooth muscle

Mechanism of action

Drugs may act by altering calcium ion flow, affecting neurotransmitter release, or modulating smooth muscle contraction.

Biological functions

Muscle contractionPeristalsisSegmentationTransport of substances through the digestive tract

Disease associations

Gastrointestinal disorders (e.g., irritable bowel syndrome, bowel obstruction)Inflammation

Safety considerations

Side effects of drugs affecting bowel smooth muscle can include constipation, diarrhea, or changes in bowel habits.

Interacting drugs

anticholinergics

2 more in the full profile.

Biomarkers

None specific to bowel smooth muscle itself, but biomarkers for related conditions may exist.

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