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The brachial plexus is a network of nerves composed of five roots (ventral rami of spinal nerves C5-T1) that merge into three trunks (superior, middle, and inferior)[1][3][4][8]. Roots refer to the initial anterior rami that exit the spinal cord, while trunks are formed when roots combine: C5 and C6 form the superior trunk, C7 continues as the middle trunk, and C8 and T1 join as the inferior trunk[4][5]. These structures provide motor and sensory innervation to the upper limb. Damage results in predictable patterns of weakness and numbness in the upper extremity corresponding to the affected fibers. The plexus is organized into roots, trunks, divisions, cords, and terminal branches—a classical neuroanatomical hierarchy—not a molecular, enzymatic, or receptor target[1][3][4][8]. The brachial plexus trunks/roots are neuroanatomical regions and not molecular targets or receptors; thus, the request for pharmacological/biomolecular data does not directly apply. Any extraction engine should flag this as an anatomical target with limited applicability to drug-target structure/function data[1][3][4][6][7][8].
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