Brain-enriched guanylate kinase-associated protein (BEGAIN)

The brain-enriched guanylate kinase-associated protein (BEGAIN) is a cytosolic protein mainly expressed in the brain, where it likely supports or maintains the structure of the postsynaptic density (PSD) in neurons[1]. The PSD is a protein-dense specialization found at the postsynaptic membrane of synapses and is crucial for synaptic signaling and plasticity. Although BEGAIN is closely associated with this structure, its detailed molecular function remains incompletely characterized. BEGAIN is not classified as a receptor, enzyme, transporter, or transcription factor, and there are no known interacting drugs, disease associations, or biomarker roles documented in public antibody or structural protein databases[1]. If you require more detailed protein sequence or structural data, refer to specialized resources such as UniProt, NCBI Gene, or antibody product databases under "KIAA1446" or "BEGAIN."

Other names

BEGAINKIAA1446brain-enriched guanylate kinase-associated proteinbrain-enriched guanylate kinase-associated homolog