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The **brain regions controlling swallowing function** comprise an integrated network of cortical, subcortical, and brainstem structures responsible for the precise, coordinated muscular movements necessary for swallowing. Major involved regions include the **primary motor cortex**, **primary sensory cortex**, **supplementary motor area**, **cingulate cortex**, **insula** (especially anterior and posterior insular cortices of both hemispheres), **internal capsule**, **basal ganglia**, and the **brainstem swallowing centers** (particularly in the medulla oblongata). Control involves both voluntary and reflex phases with extensive sensorimotor integration. Lesions in these regions (especially post-stroke) are strongly associated with neurogenic dysphagia, making them important for understanding clinical swallowing disorders but not considered molecular drug targets.
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