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Target intelligence / Profile preview
Breast cancer associated ESR1 regulating natural antisense transcript 1 (BNAT1)
- Target
- BNAT1
- Molecular classification
- Other (long non-coding RNA, lncRNA)
01
Overview
Breast cancer associated ESR1 regulating natural antisense transcript 1 (BNAT1) is a long non-coding RNA (lncRNA) associated with breast cancer, specifically implicated in regulating the expression of ESR1, which encodes the estrogen receptor alpha[1][3][7][9]. BNAT1 is not a protein, receptor, enzyme, or traditional drug target, but rather a regulatory RNA molecule that may play a role in the transcriptional modulation of genes relevant to breast cancer, potentially affecting tumor biology through its influence on ESR1 expression[1][7][9][5]. To date, there is limited evidence for direct therapeutic targeting, approved drugs, or recognized biomarker or safety concerns for BNAT1, but its association with breast cancer suggests it may be relevant for ongoing research in the context of cancer gene regulation[9].
- Other names
- LL21NC02-21A1.1breast cancer natural antisense transcript 1
02
Biological functions
Transcriptional regulationRegulation of ESR1 (estrogen receptor 1) expression
03
Disease associations
Cancer
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