Target intelligence / Profile preview

Broad array of surface proteins, membrane proteins, polysaccharides, and other exposed antigens on Salmonella enterica and Mycoplasma hyopneumoniae

Molecular classification
Adhesins, Lipoproteins, Proteases, Outer membrane proteins, Polysaccharides, Secreted proteins, hypothetical proteins, moonlighting cytosolic proteins relocated to the surface
01

Overview

This entry comprises the collective surface molecules exposed to the host immune system or environment by the pathogens Salmonella enterica and Mycoplasma hyopneumoniae, including a wide variety of surface proteins (e.g., adhesins, lipoproteins, proteases), membrane proteins, and polysaccharides (e.g., LPS, capsules). Each surface molecule often possesses distinct structural, immunomodulatory, and adhesive functions, and many are primary targets for host immunity, diagnostic assays, drug development, or vaccine design. The surfaceome of both bacteria is exceptionally diverse, shaped by post-translational modifications, proteolytic events, and genetic variability, making it a rich source of potential targets and simultaneously complicating efforts for therapeutic targeting or biomarker selection.

Other names
Surface antigens of Salmonella entericaSurface antigens of Mycoplasma hyopneumoniaeBacterial surface proteinsBacterial membrane proteins
02

Mechanism of action

Inhibition of adhesion; Induction of bactericidal immunity; Direct antibacterial activity; Blockade of virulence mechanisms

03

Biological functions

Adhesion to host cellsImmune evasion and modulationPathogenesis and virulenceBiofilm formationHost immune signaling and inflammationTransport of molecules
04

Disease associations

InfectionInflammationPotential roles in chronic infection or immune-mediated sequelae
05

Safety considerations

Antigenic variabilityCross-reactivityAdverse immune reactionsIncomplete protection
06

Interacting drugs

Antibodies

2 more in the full profile.

07

Biomarkers

Antigen detectionImmune signatures

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