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Bromelain

Molecular classification: Enzyme, Protease, Cysteine protease, Thiol endopeptidase

Overview

Bromelain is a mixture of proteolytic enzymes extracted from the pineapple plant (*Ananas comosus*). It is a cysteine protease that catalyzes the hydrolysis of peptide bonds. It exhibits anti-inflammatory properties and is being investigated for anticancer potential.

Other names: Stem bromelain (SBM)Fruit bromelain (FBM)

Mechanism of action

Hydrolyzes internal peptide bonds in proteins via nucleophilic attack by the thiol group of its active-site cysteine residue.

Biological functions

Protein hydrolysisAnti-inflammatory activity

Disease associations

InflammationCancer (research)

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