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Bronchial glandular epithelium

Molecular classification
Other
01

Overview

Bronchial glandular epithelium refers to the cellular lining of submucosal glands within the bronchial wall of the respiratory tract. It consists primarily of mucous cells and serous cells, supported by myoepithelial cells, all derived from epithelial origin. These cells secrete mucus and serous fluid into the airways, contributing to the airway surface liquid, which plays a critical role in humidifying inhaled air, trapping inhaled particles, and maintaining airway hygiene through mucociliary clearance. Dysfunction or hyperplasia of the bronchial glandular epithelium is implicated in diseases such as asthma, chronic bronchitis, and cystic fibrosis, due to abnormal mucus production and secretion[3][4][5][8]. Bronchial glandular epithelium is not a single molecule or protein, nor a canonical pharmacological target, but a morphological tissue structure. If you seek drug targets, you should instead reference specific cell-surface receptors, ion channels, or proteins expressed by these epithelial cells, such as muscarinic receptors, CFTR, or mucins (e.g., MUC5B)[3][4].

Other names
bronchial gland epitheliumairway glandular epitheliumsubmucosal gland epithelium
02

Biological functions

Mucus secretionBarrier functionAirway hydrationHost defense
03

Disease associations

Chronic obstructive pulmonary disease (COPD)AsthmaChronic bronchitisCystic fibrosisOther respiratory diseases

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