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BSG antisense RNA 1 (BSG-AS1)
- Target
- BSG-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Non-coding natural antisense transcript (ncNAT)
01
Overview
BSG antisense RNA 1 (BSG-AS1) is a naturally occurring long non-coding antisense RNA transcript complementary to the BSG gene. As an lncRNA, BSG-AS1 is not translated into protein. General functions of antisense RNAs include modulation of gene expression through RNA-RNA and epigenetic interactions[1][7]. BSG-AS1 has been implicated in the regulation of biological events such as cell growth or differentiation, and its differential expression is associated with certain cancers, notably hepatocellular carcinoma[1][2]. However, BSG-AS1 is not considered a classical therapeutic target like receptors or enzymes, and no drugs are known to act directly on it. Its broader relevance is as part of a growing research focus on non-coding RNAs and their roles in disease, especially cancer[2][7].
- Other names
- BSG-AS1HGNC:55286NCBI Gene:105372233Ensembl:ENSG00000267751Various previous GeneCards identifiers (e.g., GC19M000561, see source for full list)
02
Biological functions
Regulation of gene expression (by antisense interaction with BSG gene)Potential regulation of cell growth and differentiation (general to antisense RNAs)
03
Disease associations
Cancer (specifically hepatocellular carcinoma association)
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