Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
C-C motif chemokine ligand 20 (CCL20)
- Target
- CCL20
- Molecular classification
- Chemokine, CC chemokine family, Ligand
01
Overview
C-C motif chemokine ligand 20 (CCL20) is a chemokine that acts as a chemotactic factor, primarily attracting lymphocytes and playing a role in immune responses by recruiting Th17 and Treg cells to sites of inflammation. It is involved in the formation of mucosal lymphoid tissues and exhibits antimicrobial activity against Gram-negative bacteria. CCL20's expression is induced by inflammatory stimuli and it signals through the CCR6 receptor. Dysregulation of CCL20 is implicated in autoimmune diseases and cancer progression.
- Other names
- Liver activation regulated chemokine (LARC)Macrophage Inflammatory Protein-3 alpha (MIP-3A)Exodus
02
Biological functions
ChemotaxisImmune responseRecruitment of immune cellsAntimicrobial activityTissue formation
03
Disease associations
Autoimmune diseasesInflammatory bowel diseaseRheumatoid arthritisPsoriasisMultiple sclerosisCancerTumor progression
04
Biomarkers
Potential biomarker in various diseases due to its role in inflammation and immune response
Beyond the preview
Go deeper on C-C motif chemokine ligand 20 (CCL20).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on C-C motif chemokine ligand 20 (CCL20).