C-type lectin-like 1 (CLECL1)

C-type lectin-like 1 (CLECL1) encodes a type II transmembrane protein of the C-type lectin-like family, highly expressed on dendritic and B cells[1]. It is presumed to function as a T cell costimulatory molecule promoting interleukin-4 production and possibly participates in immune response regulation[1]. However, biological details remain limited, and there is significant ambiguity in the literature; in some contexts, CLECL1 may be referenced as a pseudogene[1][3]. CLECL1 is not a validated therapeutic target, and its precise signaling properties, endogenous ligands, or clinical disease roles remain poorly characterized[3]. The broader C-type lectin-like family encompasses receptors involved in immune recognition, cell adhesion, and immunoregulation, but specifically, CLECL1’s function, mechanism, and therapeutic relevance have not been clearly defined[2][3].

Other names

DCAL1DCAL-1DC-associated lectin-1Dendritic cell-associated lectin 1CLECL1PCLECL1C-type lectin-like domain family 1 pseudogene