C-X-C motif chemokine receptor 2 pseudogene 1 (CXCR2P1)

C-X-C motif chemokine receptor 2 pseudogene 1 (CXCR2P1), corresponding to Ensembl gene ENSG00000277755, is a human gene classified as a pseudogene, meaning it does not encode a functional protein product. It is annotated as a pseudogene of the chemokine (C-X-C motif) receptor 2 (CXCR2), also known as the interleukin 8 receptor beta. As a pseudogene, CXCR2P1 is not considered a therapeutic target, nor is it associated with any pharmacological action or disease relevance as a direct protein product. Its presence is sometimes noted in genomic studies but it has no known direct cellular or signaling function. Pseudogenes may occasionally have regulatory RNA functions, but there are no established functions or disease associations for this particular pseudogene. The functional, druggable GPCR chemokine receptor is CXCR2 (C-X-C motif chemokine receptor 2, NCBI: 3579), not its pseudogene. Therefore, this entry is not a therapeutic target; it is a non-functional genetic segment derived from a chemokine receptor gene and should be indicated as an incorrect or non-actionable entry for any drug discovery or target validation purposes.

Other names

CXCR2P1Chemokine (C-X-C motif) receptor 2 pseudogene 1Interleukin 8 receptor, beta pseudogeneCXCR2PIL8RBPChemokine (C-X-C motif) receptor 2 pseudogenePseudogene for the low affinity IL-8 receptorInterleukin 8 receptor (IL8RP) pseudogene