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C1QTNF9B antisense RNA 1 (C1QTNF9B-AS1)

Target
C1QTNF9B-AS1
Molecular classification
Other (long non-coding RNA)
01

Overview

C1QTNF9B antisense RNA 1 (C1QTNF9B-AS1), also referred to as PCOTH or Prostate collagen triple helix protein, is a **long non-coding RNA (lncRNA)**. Multiple sources confirm its classification as an RNA gene, not a receptor, enzyme, or classic druggable protein target. It is expressed in various tissues, including the prostate and testis, and is predicted to have functions related to the extracellular matrix or as a structural RNA. Some studies suggest a link to prostate cancer cell growth and potential regulatory roles, but **there is little direct evidence that C1QTNF9B-AS1 functions as a therapeutic target, receptor, or enzyme**. It is not currently associated with known pharmacological modulators or established clinical biomarkers. Existing references conflate protein-coding genes (such as C1QTNF9B) and the lncRNA (C1QTNF9B-AS1), but the target described in your query matches the lncRNA, not a classic protein target[2][4][5][6][7]. Therefore, there is a conceptual error in treating "PCOTH" or "C1QTNF9B-AS1" as a classic target; it should be cataloged as a long non-coding RNA, not a protein or receptor.

Other names
PCOTHProstate collagen triple helix proteinC1QTNF9B antisense gene protein 1Pro-X-Gly collagen triple helix like repeat containingprostate collagen triple helixPCOTH_HUMANprostate and testis expressed opposite C1QTNF9B and MIPEP
02

Biological functions

Other (potential regulatory function as lncRNA, possible extracellular matrix structural association)
03

Disease associations

Cancer (prostate cancer, possible metabolic/cancer associations)Other (potentially implicated in cell growth)

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