C2 calcium-dependent domain-containing protein 4D (C2CD4D)

C2 calcium-dependent domain-containing protein 4D (C2CD4D) is a human protein encoded by the C2CD4D gene located on chromosome 1[2][4]. The protein contains a conserved C2 domain, characteristic of the C2 superfamily, which is typically involved in calcium-dependent phospholipid binding found in proteins like synaptotagmins and protein kinases C, though the specific function of C2CD4D remains unconfirmed[2]. C2CD4D is predicted to be intracellular, lacking both signal peptides and transmembrane domains[2][5]. Its expression appears restricted to certain tissues, such as the brain, intestine, and mammary gland, with reports of expression primarily in the context of certain cancers[2]. There are no established small-molecule drug interactions, known disease mechanisms, clinical biomarkers, or reported therapeutic targeting for this protein to date. Its evolutionary conservation among mammals suggests a conserved, though still unclear, function[2].

Other names

FAM148DC2 calcium dependent domain containing 4Dfamily with sequence similarity 148, member D