Target intelligence / Profile preview

C2orf74 antisense RNA 1 (C2orf74-AS1)

Target
C2orf74-AS1
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA
01

Overview

C2orf74 antisense RNA 1 (C2orf74-AS1) is a long non-coding RNA (lncRNA) transcribed from the region antisense to the C2orf74 gene on chromosome 2. As an antisense RNA (asRNA), its primary role is likely regulation of gene expression, potentially through mechanisms such as transcriptional interference, regulation of chromatin state, or RNA-RNA interactions. Unlike the C2orf74 protein-coding gene, which is associated with some autoimmune and bowel diseases, there is currently no evidence that C2orf74-AS1 itself functions as a therapeutic target, nor are any interacting drugs, mechanisms of action, or biomarkers known for it. Like other antisense lncRNAs, it may play a context-dependent regulatory role but does not serve as a canonical receptor, enzyme, or drug target. If your focus is on discovering receptors, transporters, or therapeutic protein targets, C2orf74-AS1 does not meet these criteria. It is listed in gene databases under non-coding RNA categories but is not established as a druggable therapeutic target as of current knowledge.

Other names
AC016747.2C2orf74-DTC2orf74 divergent transcriptC2orf74-AS1
02

Biological functions

Regulation of gene expression (via antisense RNA mechanisms)
03

Disease associations

Other (no direct evidence for a disease role; gene locus of C2orf74, which is different, is linked to colorectal cancer and autoimmune diseases)

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