Cadherin 12 pseudogene 2 (CDH12P2)

Cadherin 12 pseudogene 2 (CDH12P2) is one of several non-functional genomic elements derived from the parental Cadherin 12 gene, a type II classical cadherin expressed predominantly in the brain and involved in cell-cell adhesion during neuronal development[1][7]. Pseudogenes like CDH12P2 may not encode functional proteins but can regulate gene expression by acting as competitive endogenous RNAs (ceRNAs) or miRNA sponges—modulating processes such as cancer progression and epithelial-to-mesenchymal transition (EMT)[2]. CDH12P2 is located in the 5q13.2 region, potentially influencing genome stability and has been implicated, though not confirmed, in conditions like spinal muscular atrophy (SMA) due to locus effects[2]. There is no evidence for direct drug targeting, therapeutic intervention, or specific safety concerns tied to CDH12P2[5][2].

Other names

C41-CADCDH12PBr-cadherin pseudogeneCadherin 12 (N-cadherin 2) pseudogene 2CDH12P2

Not applicable. No drugs directly target this pseudogene.