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Cadherin related family member 1

Molecular classification: Cadherin superfamily, Cell adhesion molecule, Transmembrane protein

Overview

Cadherin related family member 1 (CDHR1) is a protein encoded by the *CDHR1* gene in humans. It belongs to the cadherin superfamily and is specifically expressed in photoreceptor cells of the retina, playing a crucial role in maintaining their structural integrity. Mutations in *CDHR1* are linked to autosomal recessive retinal dystrophies, including cone–rod dystrophy and retinitis pigmentosa.

Biological functions

Cell-cell adhesionMaintenance of photoreceptor outer segment structureRetinal organization

Disease associations

Retinal dystrophiesCone-rod dystrophyRetinitis pigmentosa

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