Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Cadherin-related family member 4 (CDHR4)
- Target
- CDHR4
- Molecular classification
- Calcium-dependent cell adhesion molecule, Cadherin superfamily (non-classical cadherin), Type-I transmembrane protein
01
Overview
Cadherin-related family member 4 (CDHR4) is a predicted calcium-dependent cell adhesion protein belonging to the cadherin superfamily. Like other members, it is thought to enable homophilic cell-cell adhesion and contribute to tissue organization, particularly through mediating calcium-dependent interactions at the plasma membrane. CDHR4 preferentially interacts with itself and is mainly located in the plasma membrane. It is structurally characterized by extracellular cadherin domains that bind Ca²⁺ ions, essential for its adhesive function. While detailed tissue-specific roles and biological functions are less characterized compared to classical cadherins, it is a paralog of CDH16 and has been associated with the rare disorder Mirror Movements 1. No specific drugs, safety concerns, or biomarker utility are documented for CDHR4 at present.
- Other names
- CDHR4CDH29 (previous symbol)Cadherin-related family member 4
02
Mechanism of action
None established for drugs (no interacting drugs)
03
Biological functions
Cell adhesionCalcium ion bindingPutative role in sorting heterogenous cell types (by similarity to other cadherins)Likely membrane organization
04
Disease associations
Mirror Movements 1
Beyond the preview
Go deeper on Cadherin-related family member 4 (CDHR4).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Cadherin-related family member 4 (CDHR4).