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Target intelligence / Profile preview
Calcium beta-hydroxy-beta-methylbutyrate (HMB-Ca)
- Target
- HMB-Ca
- Molecular classification
- Other, small molecule, dietary supplement ingredient
01
Overview
Calcium beta-hydroxy-beta-methylbutyrate is the calcium salt form of beta-hydroxy-beta-methylbutyric acid (HMB), a naturally occurring metabolite of the amino acid leucine. As a dietary supplement, it is used to support muscle preservation and recovery, notably in sports nutrition or conditions causing muscle wasting. It is not a biological macromolecule, receptor, enzyme, transporter, or conventional drug target. Supplementation provides bioavailable HMB, which may modulate protein metabolism, but the compound itself is not a recognized molecular target for therapeutic drugs[1][2][4][5].
- Other names
- Calcium HMBCalcium 3-hydroxy-3-methylbutyrateButanoic acid, 3-hydroxy-3-methyl-, calcium saltHMB-CaCalcium β-hydroxy β-methylbutyrate
02
Biological functions
Othernutritional supplementmuscle metabolism modulator via indirect metabolite effects
03
Disease associations
Othersports nutritionmuscle wasting disordersnot a direct therapeutic molecular target for major disease classes
04
Safety considerations
Gastrointestinal tolerance in high dosespossible mineral imbalances with excess calcium intaketypical for supplements
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