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VN2R9P, also known as the calcium-sensing receptor pseudogene, is a genomic locus classified as a pseudogene related to the calcium-sensing receptor (CaSR). Unlike its functional homolog CaSR, VN2R9P does not encode a functional receptor and is not involved in calcium sensing, signaling, or any established biological processes. No drugs target this pseudogene, and it does not have any known clinical, diagnostic, or therapeutic use[8]. Key consideration: - It is important not to confuse this pseudogene (VN2R9P / calcium-sensing receptor pseudogene) with the functional **calcium-sensing receptor (CaSR)**, which is a class C G-protein-coupled receptor involved in calcium homeostasis and acts as a drug target in certain diseases[1][2][5][6]. - As a pseudogene, VN2R9P is not considered a therapeutic target, nor does it have known biological or disease associations.
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