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Calmodulin 2 pseudogene 1 (CALM2P1) is a pseudogene—a non-coding genomic sequence highly homologous to the protein-coding calmodulin 2 (CALM2) gene, but lacking the ability to code for a functional protein product[1][3][4]. CALM2P1 is not characterized as a functional gene or protein, has no direct biological, pharmacological, or clinical significance, and is not considered a drug target. In humans, several pseudogenes related to CALM2 exist and may be annotated on different chromosomes[1]. Any meaningful drug targeting, mechanism of action, or disease association involves functional calmodulin (i.e., CALM1, CALM2, or CALM3), not the pseudogene. If you intended to query the druggability or biology of calmodulin 2 (CALM2) rather than its pseudogene, please clarify and I can provide detailed data for the canonical calmodulin 2 target.
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