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Caloric density of consumed foods refers to the number of calories present in a given weight or volume of food, typically expressed as calories per 100 grams or per pound[1][2][4]. Foods with high caloric (or energy) density contain more calories for their weight compared to low-calorie-density foods. This concept is widely used in nutrition science and diet planning to help individuals manage body weight by choosing foods that provide satiety with fewer calories[1][2][4]. High-calorie-density foods are often rich in fats and/or low in water content, while low-calorie-density foods tend to be higher in water and fiber content[1][2][3]. While caloric density is an important dietary metric for health outcomes such as obesity prevention or healthy weight gain, it does not represent a specific molecule, receptor, enzyme, transporter, or other canonical therapeutic target class[1][2].
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