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Calpain-13 (CAPN13)
- Target
- CAPN13
- Molecular classification
- Enzyme, Cysteine protease, Calcium-activated neutral protease, Member of the calpain family, Probable non-lysosomal thiol-protease
01
Overview
Calpain-13 is a nonlysosomal, calcium-activated cysteine protease that contributes to proteolysis, cell proliferation, and is associated with muscular dystrophy, retinal disease, and some cancer-related processes.
- Other names
- Calpain-13CAPN13CANP 13FLJ23523Calcium-activated neutral proteinase 13calpain 13CANP13Gm943
02
Biological functions
ProteolysisCalcium-dependent cysteine-type endopeptidase activityRegulation of cell proliferation
03
Disease associations
Limb-girdle muscular dystrophy type 2AExudative vitreoretinopathy 2Carcinoma in situ, epithelial cancer in situUlcerative colitis
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