Calponin 2 pseudogene

ENSG00000277869 encodes a pseudogene related to the calponin 2 gene, sometimes described as "calponin 2 pseudogene" or by similar names. Pseudogenes are non-functional genomic DNA sequences similar to normal genes but typically unable to encode a functional protein, often due to accumulated mutations or lack of regulatory elements. While the functional calponin 2 gene (CNN2) is implicated in actin binding, cytoskeletal regulation, and multiple biological processes—including smooth muscle contraction, cell migration, and potentially cancer biology—pseudogenes such as ENSG00000277869 do not produce functional protein products and are not considered therapeutic drug targets or biologically active themselves. There is no evidence of disease association, druggability, or biomarker status for this pseudogene[2][4][7].