Calponin 2 pseudogene 4 (CNN2P4)

Calponin 2 pseudogene 4 (CNN2P4) is a pseudogene related to the protein-coding gene CNN2 (calponin 2). Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they usually lack the regulatory elements or have disabling mutations that prevent them from encoding functional proteins[5]. CNN2P4 does not produce a functional protein and is not considered a therapeutic target. Several pseudogenes related to CNN2 exist on various human chromosomes, reflecting the historical duplication events in the genome. There is no evidence that CNN2P4 has a biological function, is involved in disease, or is targeted by drugs[5]. The CNN2 gene encodes calponin 2, a cytoskeletal protein with roles in smooth muscle contraction, cell migration, and immune cell function, and is connected to disease processes such as cancer and fibrosis[1][5][6]. However, pseudogenes like CNN2P4 do not produce the calponin 2 protein or contribute to these functions. CNN2P4 should not be treated as a drug or therapeutic target. There is no evidence in scientific literature or molecular databases that CNN2P4 is druggable, functional, or clinically relevant as a biomarker or for safety monitoring[5]. If your intent was to find data on the protein-coding gene, refer to calponin 2 (CNN2), not CNN2P4.

Other names

Calponin II pseudogene 4CNN2 Pseudogene 4