Target intelligence / Profile preview

Neoplasm (Tumor)

Target
Tumor
Molecular classification
Cell-of-origin patterns, Molecular subtypes (e.g., EBV-positive, MSI, genomically stable, chromosomal instability), Histological classifications
01

Overview

"Tumor" is not a specific molecular target or receptor but a general term for abnormal tissue growth. Tumors are classified based on molecular characteristics, histology, tissue type, or anatomic origin. Modern cancer research focuses on molecular classification of tumors to develop targeted therapies. These classifications include cell-of-origin patterns, genetic mutations, protein expression, and other molecular features that help determine appropriate treatment strategies. Molecular classification has revealed similarities among histologically or anatomically related cancer types, providing a basis for focused pan-cancer analyses and therapeutic development.

Other names
CancerNeoplasiaMalignancyGrowth
02

Mechanism of action

Blocking formation of new blood vessels; Attacking specific proteins on cancer cell surfaces; Disrupting cell signals; Disrupting normal cell functions

03

Biological functions

Cell proliferationAngiogenesisMetastasisImmune evasionAltered metabolism
04

Disease associations

Cancer (various types including gastric, breast, kidney, squamous cell carcinomas)
05

Interacting drugs

bevacizumab

5 more in the full profile.

06

Biomarkers

Genetic mutations (e.g., TP53, PIK3CA, CDKN2A)Protein expression patternsDNA methylation patternsmiRNA expression profiles

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