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Target intelligence / Profile preview
Candida albicans Antigens (N/A)
- Target
- N/A
- Molecular classification
- Glycoprotein, Polysaccharide, Protein, Pathogen-Associated Molecular Pattern (PAMP)
01
Overview
Candida albicans antigens are components of the fungus that interact with the host immune system, triggering both protective and pathological responses. Key antigens include cell wall mannans/mannoproteins, Als family proteins, and Hyr1 protein. These antigens are recognized by innate immune cells (e.g., dendritic cells, NK cells) via PRRs and initiate adaptive immune responses involving T-cells and B-cells. Immunomodulation via these antigens can be exploited for vaccine development or targeted therapies to enhance antifungal immunity or block fungal immune evasion.
- Other names
- C. albicans antigensCandida antigensFungal antigens (C. albicans)
02
Mechanism of action
N/A
03
Biological functions
Immune system activationT-cell activationB-cell activationComplement activationDendritic cell maturationNK cell modulationInnate immune responseAdaptive immune responseImmunomodulation
04
Disease associations
CandidiasisInfectionInflammationImmunopathology
05
Safety considerations
Potential for inducing inflammatory responsesRisk of hypersensitivity reactionsImmune evasion strategies employed by C. albicans
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