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Candida albicans Morphogenesis Pathway
- Molecular classification
- Signaling pathway, Regulatory network
01
Overview
The Candida albicans morphogenesis pathway refers to the complex network of molecular and cellular processes that enable this fungal pathogen to switch between different morphological forms, primarily yeast and hyphal states. This dimorphic transition is central to the organism’s virulence, tissue invasion, immune evasion, and biofilm formation. Key signaling pathways include cAMP-PKA, MAPK/Cph1, Rim101, and TOR kinase, which are regulated by environmental cues and transcription factors such as Efg1, Cph1, and Nrg1.
- Other names
- Candida albicans DimorphismCandida albicans Yeast-Hyphal TransitionCandida albicans Filamentation Pathway
02
Biological functions
Morphological transitionVirulence regulationBiofilm formationTissue invasionImmune evasionEnvironmental adaptation
03
Disease associations
InfectionCandidiasisOpportunistic infection
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