Capicua transcriptional repressor pseudogene 12 (CICP12)

Capicua transcriptional repressor pseudogene 12 (CICP12) is a non-protein-coding pseudogene related to the functional capicua transcriptional repressor (CIC)[1][4]. Pseudogenes such as CICP12 arise from duplication or mutation of functional genes and typically do not produce functional proteins or have biological activity. This gene is not involved in signal transduction, cell cycle regulation, or any known physiological or pathological process. It should not be confused with the closely related but distinct CIC gene, which encodes a transcriptional repressor with important roles in neurodevelopment and cancer[2][3][5]. Important distinction: - The functional protein is encoded by the CIC gene, not CICP12. The CIC gene is a transcriptional repressor implicated in brain development and cancer, whereas CICP12 is only a pseudogene with no known function[1][2][3][4][5]. - If seeking data for a drug target or therapeutic receptor/transcription factor, refer to the CIC gene/protein, not CICP12. - There is nothing to suggest CICP12 itself is misspelled, but it is commonly confused with CIC due to the name similarity.

Other names

Capicua homolog pseudogene 12CICP12Gene IDs: NCBI 100420224, Ensembl ENSG00000225270

None (no known mechanism; not a protein product)