Capicua transcriptional repressor pseudogene 20 (CICP20)

Capicua transcriptional repressor pseudogene 20 (CICP20) is a human pseudogene belonging to the family of capicua transcriptional repressor pseudogenes. Pseudogenes are genomic DNA sequences that resemble functional genes but are generally considered non-functional due to mutations or lack of regulatory elements required for expression. There are no functional proteins, known therapeutic implications, or disease associations reported for CICP20—it does not encode an active transcriptional repressor and is not a characterized drug target or biomarker. The *functional* Capicua transcriptional repressor (gene symbol: CIC) is a high mobility group (HMG)-box containing transcriptional repressor protein implicated in several physiological and disease processes, including neurodevelopment and cancer. CICP20 is one of several pseudogenes for CIC and does not share these functional attributes. No information is available regarding its utility in therapeutics, diagnostics, or as a biomarker, thus it is not considered a target by pharmacological definitions. This entry is most accurately classified as a genomic pseudogene and not a target molecule or receptor.

Other names

HGNC: 48830NCBI Gene: 100129050Ensembl: ENSG00000235955