Target intelligence / Profile preview

Capicua transcriptional repressor pseudogene 22 (CICP22)

Target
CICP22
Molecular classification
Other (Pseudogene)
01

Overview

Capicua transcriptional repressor pseudogene 22 (CICP22) is classified as a pseudogene on human chromosome 22 and is similar in sequence to the protein-coding gene "Capicua transcriptional repressor" (CIC), a high-mobility group box (HMG-box) transcriptional repressor important in developmental regulation and cancer. Unlike functional CIC genes, pseudogenes like CICP22 are usually considered nonfunctional and do not encode a protein. A subset of pseudogenes may be transcribed, but there is currently no evidence that CICP22 has any biological activity or role in disease; it is not considered a drug target. If you are searching for information about the functional Capicua protein (CIC), that is a transcriptional repressor implicated in oncogenesis and neural development. However, CICP22 itself does not share those characteristics or applications.

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