Capicua transcriptional repressor pseudogene 28 (CICP28)

Capicua transcriptional repressor pseudogene 28 (CICP28) is classified as a pseudogene, specifically related to the capicua transcriptional repressor (CIC) gene family[1][3][5]. Pseudogenes are genomic DNA sequences similar to normal genes, but they typically lack the ability to code for functional proteins due to disruptive mutations or absence of regulatory elements[3][5]. Unlike its functional counterpart, CIC—which is a high mobility group (HMG)-box transcriptional repressor involved in development and disease—CICP28 does not encode a functional protein or RNA with a known biological role[1][3][5]. There is no current evidence linking CICP28 with any validated disease role, drug interaction, or functional mechanism in biology or medicine[1][3]. Thus, it should not be considered a true molecular target. Key points: - Capicua transcriptional repressor pseudogene 28 is a nonfunctional pseudogene derived from the CIC gene[1][3][5]. - Pseudogenes like CICP28 generally do not encode proteins or serve as therapeutic targets[1][3][5]. - CICP28 has no known biological function, disease association, or role as a drug target[1][3]. - The entry is most relevant as a member of a large pseudogene family arising by gene duplication and inactivation, not as a clinically actionable or druggable entity[1][3][5]. If further details such as potential regulatory roles or expression profiles are discovered in future research, this information may require updating, but as of current knowledge, CICP28 should not be considered a molecular target or therapeutic gene[1][3].

Other names

CICP28