Carbonyl reductase 3 pseudogene

Carbonyl reductase 3 pseudogene (ENSG00000257738; LOC100419293) is classified as a pseudogene—an inactive genetic sequence related to the functional carbonyl reductase 3 (CBR3) gene, which encodes an NADPH-dependent oxidoreductase enzyme. Unlike CBR3, the pseudogene does not produce a functional protein and is not a target for drugs or therapies. Pseudogenes such as this one sometimes play regulatory roles in gene expression by interacting with RNA or DNA, but there is no evidence of such function for this specific pseudogene. Therapeutic interest, disease associations, drug interactions, and biomarkers are all connected solely to the functional CBR3 protein, not its pseudogene. The presence of this entry may reflect database inclusion of genetic elements that are present in the genome but not actionable in pharmacology or medicine. For structured data purposes, this entry should be flagged as not a conventional drug target (is_target = false), and potential confusion with the active CBR3 gene should be explicitly noted (is_incorrect = true).

Other names

LOC100419293carbonyl reductase 3 pseudogeneCBR3P