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Target intelligence / Profile preview
Carboxymethylenebutenolidase homolog pseudogene (LOC100132669)
- Target
- LOC100132669
- Molecular classification
- Other (pseudogene; not a protein-coding gene or member of functional gene families like enzymes, receptors, etc.)
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Overview
The carboxymethylenebutenolidase homolog pseudogene (LOC100132669; ENSG00000225304) is a non-protein-coding genetic sequence in humans homologous to the functional carboxymethylenebutenolidase (CMBL) enzyme gene. CMBL is a cysteine hydrolase of the dienelactone hydrolase family involved in the activation of certain drug prodrugs (such as olmesartan medoxomil, faropenem medoxomil, and lenampicillin). However, the pseudogene LOC100132669 does not encode any functional protein and thus does not contribute to these biological activities. All drug metabolism functions, disease associations, molecular activity, and related research refer to the protein-coding gene CMBL (e.g., ENSG00000164237), not the pseudogene LOC100132669. The pseudogene itself holds no therapeutic target status and is not relevant for drug interactions or biomarker development. If you seek information about the actionable therapeutic target, search for "Carboxymethylenebutenolidase homolog (CMBL)" rather than this pseudogene.
- Other names
- Carboxymethylenebutenolidase homolog pseudogeneLOC100132669ENSG00000225304
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